Purple urine bag syndrome in benign prostatic hyperplasia patient

TRYPTOPHAN IN DIET INDOLE INDOXYL SULPHATE (INDICAN) URINARY INDOXYL SULPHATE INDOXYL INDIGO BLUE VIOLET INDIRUBIN RED VIOLET PURPLE URINARY BAG GIT PORTAL VENOUS SYSTEM BLOOD/SERUM RENAL SYSTEM Deamination (Intestinal Bacteria) Reaches liver through portal vein Hepatic conjugation Constipation Slow gut motility Bacterial overgrowth ++ Impaired renal function CKD/DM ++ More indican in serum so More in urine URINARY TRACT Bacterial sulphatase & phosphatase Bacteria Female sex Dehydration ++ High pH Alkaline Low oxygen Anaerobic medium Chronic indwelling catheter METABOLIC PATHWAY & PROPOSED PATHOPHYSIOLOGICAL MECHANISM